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Downstream Process Development Associate
Ref No.: 20-00184
Category: Biotechnology
Location: Pearl River, New York
As a Downstream Process Development Associate, the incumbent will report directly to the Head of Process Development and will be responsible for the day to day design and execution of laboratory experiments to develop scalable downstream processes for the purification of recombinant protein or viral vectors.

Responsibilities:
  • Design and execute laboratory experiments to develop scalable downstream process for the purification of recombinant protein or viral vectors
  • Knowledge in recombinant protein or viral vector purification processes, including chromatography process (i.e. IEX, affinity, SEC, reversed phase), ultrafiltration / diafiltration, process scale up, scale down model qualification, viral and depth filtration
  • Ability to optimize processes for product purity, recovery, impurity removal, and cost reduction
  • Assist in tech transfer of small-scale process to contract manufacturing organization (CMO) for scale-up
  • Assists with preparing protocols, reports, and test methods
  • Ability to foster a collaborative work environment with internal and external partners

Qualifications:
  • PhD in Biotechnology, Protein Chemistry, Biochemistry or Chemical/Biochemical Engineering with minimal 2-4 years or MS with minimal 6+ years of relevant industrial experience
  • Good foundation in general scientific practice, principles, and concepts of discipline.
  • Basic knowledge of GMP/GLP regulations in cGMP/cGLP manufacturing environment preferred.
  • Good lab skills.
  • Good problem-solving and critical thinking skills.
  • Effective communication skills.
  • Good MS Excel and Word skills.
  • Excellent organization skills.
  • Ability to execute tasks and studies based on the deliverable timeline.
  • Ability to analyze and summarize routine scientific data.
  • Ability to function in a rapidly changing environment.