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Scientist IV
Ref No.: 18-24894
Location: Spring House, PA 19477, Pennsylvania
In this laboratory-based position, the candidate will join a group of scientists within the ImmunoPharmacology group to conduct in-vivo/ex-vivo studies to support the discovery and development of Client large and small molecule therapeutics targeting immunological diseases. The position offers an exciting opportunity to engage in the discovery of Client therapeutics for unmet medical needs.

The candidate will:
Design and execute non-routine experiments with minimal supervision
Independently analyze and interpret experimental results and draft protocols, SOPs, technical reports etc.
The ability to generate and maintain experimental data in an electronic laboratory notebook in a highly organized manner is essential
Demonstrate the ability to interface effectively and positively with all levels of colleagues in research and non-clinical functions
Independently present/defend scientific findings in cross-functional project teams/initiatives

The candidate should have a BS/MS or PhD degree in biological sciences with experience in pharmacology and/or immunology and relevant work experience (a minimum 3-5 years with BS/MS degree, or 2-3 years with a PhD) in drug discovery/Immunology research. The individual will be actively involved in planning and executing pharmacology studies involving in vitro/ex vivo laboratory work. Experience with multicolor flow cytometry, FACS CANTO, Luminex assays, MSD ELISA, QPCR and immunoassays are must. Hands-on experience with mechanistic animal models of inflammation/autoimmunity/immune modulation is a plus. The successful candidate will also have strong quantitative skills, be familiar with laboratory instrumentation, data and statistics software (PRISM) spreadsheet (Excel) management. The individual should have good organizational skills and the ability to manage his/her workload and prioritize tasks. Proven ability to plan execute scientific research and ability to work well in a highly matrixed, interactive environment is critical. Successful candidate should be detailed-orientated and a quick learner. Essential functions also include the demonstration of oral, written and interpersonal skills including the ability to document and effectively communicate experimental hypothesis, interpretation of results and articulate potential next steps.